MLB.com's No. 43 prospect smacked two homers and fell a double shy of the cycle Tuesday, leading the Double-A Corpus Christi Hooks to an 8-2 win over the Midland RockHounds.
It was the first baseman's third career multi-homer game and raised his average to .377 in 17 Texas League contests.
Singleton plated the game's first run with an RBI single to center field in the opening inning, then took A's No. 4 prospect Sonny Gray (1-2) deep leading off the fourth.
The Astros' top prospect legged out a two-out RBI triple in the fifth to make it 5-2 and pulled another solo shot down the right-field line off Brett Hunter in the eighth.
It completed the California native's second career four-hit game and first in nearly two years. The 20-year-old also went yard twice for Class A Lakewood on June 20, 2010 and duplicated the feat for Class A Advanced Clearwater last June 23. The four RBIs were two short of the personal best he set last June 21.
"I'm just going out there trying to hit the ball hard," Singleton told the Corpus Christi Caller-Times. "Wherever it lands is wherever it lands. It's always nice to hit home runs.
"I'm definitely starting to find my swing. I feel like I'm taking better cuts at the plate and it just goes from there. I've tried to slow things down in the batter's box and working in the cage, but there haven't been major adjustments."
Singleton ranks among the Texas League leaders in several offensive categories. His .377 average is second to teammate Brandon Barnes (.394), while his .457 on-base percentage is No. 2 behind Midland's Shane Peterson. Acquired from the Phillies in last year's Hunter Pence trade, the 2009 eighth-round pick also is third with 11 extra-base hits and 15 runs scored.
Hooks starter Jose Cisnero (2-1) struck out 12 and allowed two unearned runs on three hits and four walks over five innings for the win. Arcenio Leon and Adalberto Flores combined for four scoreless frames.
Gray gave up five runs on seven hits over six innings, walking two and striking out four.